From my understanding, at least one other necessary component is dxvk, and that wine is not enough.
If I dont use lutris or some other manager, how can I game on linux? do I have to configure dxvk? do I need soemthing else too? vulkan?
Is there a guide that explains it?
Don’t use vanilla wine, use Wine-GE, which is basically Proton-GE, but designed for non-Steam launchers like Lutris.
Wine-GE (and Proton-GE) already includes DXVK and VKD3D btw.
You may also need to install proprietary codecs. Look up how to install the full ffmpeg and gstreamer plugins, or just “codecs” for your distro.
As to what else you require specifically, that really depends on your distro, graphics card, and how you’re launching your games.
The Arch Wiki covers some of this stuff, but note that some of it may not be applicable to you if you’re not using Arch (or an Arch-based distro). In saying that, a lot of it is applicable, but the package names may be different in your distro so you’ll need to look that up on your own.
Alternatively, you wouldn’t need to worry about any of this stuff if you go for a distro that’s optimised for gaming, such as Nobara.