LMDE didn’t install the DKMS modules on my kid’s PC, so the nVidia drivers never loaded after a new kernel got installed. I do enough tech support at work so we chucked Pop!_OS on the PC (and set it up with btrfs and timeshift-autosnap) instead. No more problems.

May not be a problem with mainline Mint, of course, but there are weirdos like me who prefer the Debian edition.